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Cmia hiv test window period3/11/2023 Specimens that were negative by CMIA (S/CO<1) were all negative by HIV-RNA testing. When CMIA signal-to-cutoff ratio (S/CO) was 11.26, the sensitivity and specificity were highest (100%, 99.43%), and the area under the ROC curve (AUC) was 0.998. False-positive results were more common for women affected by clinical interfering factors (e.g., kidney disease, tumors) than for men (80.95% vs. The HIV Ag/Ab CMIA screening results were consistent with those obtained by Western blot and HIV-RNA testing, and had an accuracy of 99.74% (Kappa index=0.98). The present study investigated the clinical effectiveness of HIV antigen/antibody (HIV Ag/Ab)combination screening by chemiluminescence microparticle immunoassay (CMIA) in over 88,000 samples from an HIV low-prevalence area of Beijing, China. However, concerns have been raised over the potential for false-positive results in antigen-antibody combination assays. Human immunodeficiency virus (HIV) screening assays have improved from single-antigen detection to detection of antigen-antibody combinations.
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